Treatment

Understanding Radiofrequency Ablation (RFA) of Liver Tumors

Choose a preferred language

Radiofrequency ablation (RFA) is a way to treat small liver tumors. RFA uses heat to kill the tumor cells. A high-frequency electrical current is sent into the tumor through a needle-like probe that holds the electrodes. This creates heat that kills the tumor cells without harming a lot of nearby healthy cells.

Outline of man showing digestive tract and liver.


 How to say it

RAY-dee-oh-FREE-kwehn-see uh-BLAY-shuhn


Why RFA of liver tumors is done

Radiofrequency ablation may be done if you can't have liver surgery. Or it may be done along with surgery.

It’s most often done if you have a small number of tumors in your liver and the tumors are small (up to about 3 centimeters across). The tumors can't be near bile ducts, major blood vessels, the diaphragm (the muscle that helps you breathe), or other nearby organs.


How RFA of liver tumors is done

This treatment is done in a hospital, and takes 1 to 3 hours. During the procedure:

  • A small tube (IV) will be put into a vein in your hand or arm. It's used to give you medicine (anesthesia) to make you relax or sleep through the treatment. A thin needle might be used to put numbing medicine into the skin where cuts will be made.

  • Grounding pads will be stuck to another place on your skin to help control the electric current that's used in RFA.

  • The healthcare provider makes a small cut (incision) in your skin. In some cases, the provider makes a few cuts and a long, thin tube with a tiny light and camera on the end (laparoscope) is put through 1 of the cuts. This helps the provider see inside your body. In other cases, the provider may make 1 large cut instead.

  • The provider puts a needle-like probe through the cut and into your liver. The probe may have 1 or many electrodes.

  • An imaging scan, like ultrasound, MRI, or CT, is used to guide the probe into the tumor.

  • When it's in the right place, electricity is sent through the electrode. This creates heat that kills the tumor cells. This is done for each tumor.

  • The tools are then taken out, and the cuts in the skin are bandaged. They seldom need stitches (sutures). The grounding pads are taken off.

  • You'll wake up in a recovery room. You may be attached to machines that keep track of your blood pressure, breathing, oxygen level, and heart rate. If needed, you'll be given medicines for pain or nausea.

  • When you fully wake up after treatment, you may be able to go home. Or you might stay in the hospital for a night or so.

  • A CT or MRI will be done soon after RFA to see if there are any tumors left in your liver. This will be repeated every 3 to 4 months to watch for new tumors. RFA can be repeated, if needed.


Risks of RFA of liver tumors

Any medical procedure carries some risk, but seldom causes problems. Possible risks of RFA include:

  • Problems from the anesthesia

  • Pain (often shoulder pain)

  • Skin burns

  • Bleeding

  • Leaking of bile from the liver

  • Infection

  • Blood clots

  • Damage to nearby organs, such as the gallbladder, bile ducts, intestines, or diaphragm

  • Damage to nearby blood vessels

  • Liver abscess, which is a pocket of infection inside the liver

  • Aches, fever, chills, delayed pain, and upset stomach (nausea) for a few days (called postablation syndrome)

Author: Wheeler, Brooke

Online Medical Reviewer: Jessica Gotwals RN BSN MPH

Online Medical Reviewer: Rajadurai Samnishanth Researcher

Online Medical Reviewer: Susan K. Dempsey-Walls RN

Date Last Reviewed: 12/01/2024

© 2000-2026 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.
user headset icon

Need Help? We're Here for You

Our Member Services team is here to help you understand your benefits, find care, or resolve concerns.

1-800-510-9132
quit smoking icon

Call NC Quitline

Need support to quit smoking, vaping, or to quit other nicotine products? You can receive support including medicines free of charge:

1-800-784-8669
car and bus icon

Schedule Transportation

Need transportation to a doctor's office, pharmacy, or other covered healthcare service? Contact us to arrange your ride.

1-800-510-9132
Stethoscope icon

Provider Directory

Need to find a provider like a Primary Care Physician, Specialist, OB/GYN, or a Psychiatrist? 

Provider Directory
Related Articles
Read article
Digestive Health
Anal Cancer: Treatment Questions

Here is a list of questions to ask your healthcare provider about treatment for anal cancer.

Read article
Digestive Health
What Is an Ileostomy?

During an ileostomy, healthcare providers either remove or disconnect your colon (large intestine), and sometimes part of the last section of your ileum (last section of your small intestine).

Read article
Digestive Health
Treating Gallstones

The gallbladder is an organ that stores bile. This is a substance that helps with digestion. Deposits in bile can clump together, creating hard, pebble-like stones. Here is information on treatment choices.

Read article
Digestive Health
Understanding Liver Transplants

During a liver transplant, your diseased or injured liver is removed. It's replaced with a healthy donor liver. Learn about the process leading up to your transplant.