Everyone feels sad or “blue” from time to time for a few days or weeks. Depression is when these feelings don't go away and they interfere with daily life. Depression is a real, serious illness, just like diabetes or heart disease. It can develop at any age. It is one of the most common mental health problems in the U.S. Depression makes you feel sad, helpless, anxious, or hopeless. It gets in the way of your life and relationships. Depression causes chemical changes in the brain that inhibit your ability to think and act. But, with help, you can feel better again.
Depression affects your whole body
Brain chemicals affect your body as well as your mood. So depression may do more than just make you feel low. You may also feel bad physically. Depression can:
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Cause trouble with mental tasks, such as remembering, concentrating, or making decisions.
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Make you feel nervous and jumpy.
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Cause trouble sleeping. Or you may sleep too much.
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Change your appetite.
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Cause headaches, stomachaches, or other aches and pains.
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Drain your body of energy.
Depression and other illness
It is common for people who have chronic health problems to also have depression. It can often be hard to tell which one caused the other. A person might become depressed after finding out they have a health problem. But some studies suggest being depressed may make certain health problems more likely. And some depressed people stop taking care of themselves. This may make them more likely to get sick.
Online Medical Reviewer: L Renee Watson MSN RN
Online Medical Reviewer: Marianne Fraser MSN RN
Online Medical Reviewer: Paul Ballas MD
Date Last Reviewed: 03/01/2025
© 2000-2026 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.
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