Treatment

Understanding Continuous Renal Replacement Therapy (CRRT)

Choose a preferred language

Continuous renal replacement therapy (CRRT) is a special type of dialysis. It’s mostly used to help very sick people whose kidneys suddenly start to fail. When the kidneys stop working, blood is no longer filtered. Waste and extra fluids then build up in the body, and chemicals get out of balance.

Like other forms of dialysis, CRRT helps filter waste and excess fluid out of the body. But it’s done more slowly and nonstop. It's often used for 24 hours or longer.


Why is CRRT done?

CRRT is done when a person's kidneys stop working and they are too medically unstable to withstand hemodialysis because of all the blood pressure and fluid shifts. They do better with slower nonstop filtering of their blood for a long period of time, such as 24 hours or more. It’s most often given to very sick people in the hospital who:

  • Have a kidney injury or kidney failure

  • Have poor blood flow

  • Need a lot of fluids and medicines, such as antibiotics, given through an IV


What happens before CRRT?

If you or a loved one needs CRRT, a healthcare provider will tell you what to expect. Talk with the healthcare provider if you have any questions or concerns.


What happens during CRRT?

CRRT is done only in a hospital. For this treatment:

  • A healthcare provider puts a special tube (catheter) into a large blood vessel, usually in the side of the neck or groin.

  • The tube is connected to a machine that holds a filter called a dialyzer.

  • The machine is turned on. The tube helps carry blood to the machine. As the blood flows through the dialyzer, waste is removed and fluid and chemicals are balanced.

  • The blood is then returned to the body through the tube.

  • The CRRT machine may alarm for several reasons. Often, the alarm is alerting the care team that it is time to change solution bags. An alarm may sound to alert the team that a position change is needed so that the machine works properly.

During CRRT, a healthcare provider may give medicines to prevent blood clots from forming. They may also give other medicines and nutrition through an IV.

CRRT is done until the kidneys start to work again. It may be needed for several days.


What happens after CRRT?

Once CRRT is stopped, you may need another type of dialysis. Talk with a provider if you have any questions or concerns.


Risks of CRRT

All procedures have risks. CRRT has these risks:

  • Heavy bleeding, infection, or blood clots forming in a blood vessel

  • Electrolyte problems

  • Drop in body temperature

  • Low blood pressure

  • Blood loss

Date Last Reviewed: 03/01/2025

© 2000-2026 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.
user headset icon

Need Help? We're Here for You

Our Member Services team is here to help you understand your benefits, find care, or resolve concerns.

1-800-510-9132
quit smoking icon

Call NC Quitline

Need support to quit smoking, vaping, or to quit other nicotine products? You can receive support including medicines free of charge:

1-800-784-8669
car and bus icon

Schedule Transportation

Need transportation to a doctor's office, pharmacy, or other covered healthcare service? Contact us to arrange your ride.

1-800-510-9132
Stethoscope icon

Provider Directory

Need to find a provider like a Primary Care Physician, Specialist, OB/GYN, or a Psychiatrist? 

Provider Directory
Related Articles
Read article
Urology
Peritoneal Dialysis (PD)

Peritoneal dialysis is a way to cleanse the blood to treat kidney failure. It uses the lining of your abdomen, called the peritoneal membrane, and a special solution (dialysate).

Read article
Urology
Ureterolysis

Pressure from a mass of tissue or scar tissue is blocking one or both of your ureters. This causes urine to back up into the kidneys instead of flowing out of the body. Ureterolysis can help treat this problem. With this surgery, the ureter is freed from the tissue that is pressing on it. The ureter is then moved to a new position away from the blockage. Read on to learn about this procedure.

Read article
Urology
Shock Wave Lithotripsy

Shock wave lithotripsy is a treatment that breaks a kidney stone into smaller pieces that are easier to pass. This treatment is also called extracorporeal shock wave lithotripsy (ESWL).

Read article
Urology
Kidney Cancer: Ablation Therapy

Ablation therapy is a type of treatment that kills cancer cells. It is a newer treatment for kidney cancer. Here's what you need to know.